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Life Extension Innovations



Resveratrol

Resveratrol is a powerful antioxidant more commonly known as the active ingredient in red wine. Resveratrol very likely has more health benefits than just protecting against heart disease thereby impacting medical fields in various ways. According to Australian researcher Lindsay Brown, the breadth of benefits is remarkable – cancer prevention, protection of the heart and brain from damage, reducing age-related diseases such as inflammation, reversing diabetes and obesity, and many more. It has long been a question as to how such a simple compound could have these effects but now the puzzle is becoming clearer with the discovery of the pathways, especially the sirtuins, a family of enzymes that regulate the production of cellular components by the nucleus (Brown 2009). The medical community has yet to jump on the resveratrol wagon (pending FDA approval) making its viability as a go-to pharmaceutical less likely. Still, the powerful health food industrial complex found a way to capitalize on the early buzz.




So, why hasn’t the scientific community moved forward in developing its commercial application? The answer is one of  a legal nature. The much-touted health benefits of red wine took a hit recently. Dipak Das, a University of Connecticut researcher who has published extensively on the positive effects of resveratrol, was found guilty on 145 counts of fabrication and falsification of data published in 11 different journals. Scientific institutional forces acted quickly to distance itself from the fallout of the investigations. Unfortunately, the move delayed any momentum gathered by researchers leading various studies. However, other researchers in the field are quick to point out that while the charges might mean the end of Das’s career, resveratrol research is alive and well. If resveratrol is to regain its promise to extend life, countervailing arguments within the scientific community will have to diminish. 

References
Brown, Lindsay (2009). The Biological Responses to Resveratrol and Other Polyphenols From Alcoholic Beverages. Alcoholism Clinical and Experimental Research, 2009; DOI: 10.1111/j.1530-0277.2009.00989.x



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